The 1980 Argentine Grand Prix was a Formula One motor race held on 13 January 1980 at the Autodromo Municipal Ciudad de Buenos Aires. It was the opening round of the 1980 Formula One season.

The race was won by Australian driver Alan Jones driving a Williams FW07. It was Jones' sixth World Championship victory. Jones won by 24 seconds over Brazilian driver Nelson Piquet driving a Brabham BT49. Finnish driver Keke Rosberg finished third driving a Fittipaldi F7.

This race was notable for the drivers threatening to boycott the event because of the appalling state of the track, which was breaking up in many spots in the infield thanks to the intense heat of a Buenos Aires summer.