The 1990 Spanish Grand Prix was a Formula One motor race held at Jerez on 30 September 1990. It was the fourteenth race of the 1990 Formula One World Championship.

The race was won by Alain Prost, driving a Ferrari, with teammate Nigel Mansell second and Alessandro Nannini third in a Benetton-Ford. Prost's Drivers' Championship rival, Ayrton Senna, took the 50th pole position of his career in his McLaren-Honda, but retired with a failed radiator, allowing Prost to close to within nine points of him in the championship with two races remaining.

The event was marred by a serious incident during Friday practice, when Martin Donnelly crashed his Lotus at the high-speed Turn 14. Donnelly was thrown from the wreckage, suffering serious injuries that ended his Formula One career. This also turned out to be the last F1 race and podium for Nannini, who severed his right arm in a helicopter crash the following week (though he would return to racing as a touring car driver), as well as the last race for the back-marking EuroBrun and Life teams.