The 2001 Brazilian Grand Prix was a Formula One motor race held on 1 April 2001 at the Autódromo José Carlos Pace in São Paulo. It was the third race of the 2001 Formula One World Championship. Starting from fifth place, McLaren driver David Coulthard won the race. Ferrari's Michael Schumacher finished second with Sauber's Nick Heidfeld third.

Michael Schumacher secured pole position by setting the quickest lap in the qualifying session. The race was interrupted after McLaren's Mika Häkkinen's engine stalled on the starting grid, prompting the safety car's deployment. When the safety car was withdrawn at the end of lap two, Williams' Juan Pablo Montoya overtook Schumacher for the lead. Montoya led the next 36 laps before he was hit by Arrows' Jos Verstappen on lap 39, forcing both drivers to retire from the race. As a result, Coulthard took the race lead and held it until the pit stops for wet-weather tyres, when the rain became heavier, and Schumacher took it for two laps until Coulthard passed him on lap 50. Coulthard led the rest of the race and won by 16.1 seconds over Schumacher, the only other driver on the lead lap.