The 2001 Malaysian Grand Prix was a Formula One motor race held at the Sepang International Circuit in Sepang, Selangor on 18 March 2001. It was the second round of the 2001 Formula One World Championship. The race was won from pole position by Michael Schumacher, driving for Ferrari. His teammate Rubens Barrichello finished second and McLaren's David Coulthard was third.

The Grand Prix was delayed and shortened from 56 to 55 laps because Giancarlo Fisichella of the Benetton team was out of position on the starting grid. When it did start, Michael Schumacher led the first two laps until he and Barrichello skidded on oil left by Olivier Panis' British American Racing car, as a tropical monsoon begin to fall. They ran into a gravel trap and Jordan driver Jarno Trulli took the lead for one lap until he and several drivers aquaplaned in the deteriorating weather. Coulthard led for 11 laps after a phase of pit stops for wet-weather tyres before Michael Schumacher passed him on lap 16. Schumacher led the remainder of the race to achieve his second victory of the season and the 46th of his career.