The 2010 Bahrain Grand Prix was a Formula One motor race held on 14 March 2010 at the Bahrain International Circuit, Sakhir. It was the opening round of the 2010 Formula One season.

The race was won by Fernando Alonso, his first as a Ferrari driver and his first F1 victory overall since the 2008 Japanese Grand Prix. His new teammate, Felipe Massa ensured a good start to the year for the team by finishing second. McLaren driver Lewis Hamilton completed the podium by finishing in third position.

All of the race had been led by polesitter and Red Bull driver Sebastian Vettel, until lap 34 when a power issue forced him to concede the lead to Alonso. This meant that he was eventually overtaken by Massa and Hamilton too, meaning that he finished in fourth place. Vettel's teammate, Mark Webber qualified sixth before finishing the race in eighth place. Michael Schumacher's first race of his return to Formula One for the Mercedes resulted in him finishing sixth, one place behind teammate Nico Rosberg. Reigning world champion Jenson Button completed his first race for the McLaren team by finishing seventh. It was also the Grand Prix debut of Nico Hülkenberg, who finished fourteenth for his team Williams.

The three new teams—Lotus, Hispania and Virgin—did not have a very successful debut race. Their six cars occupied the last six places in qualifying, and only one, the Lotus of Heikki Kovalainen, finished the race, although Jarno Trulli's Lotus was also classified in last place. As a consequence of the race, Fernando Alonso and Ferrari led their respective championships with maximum points. The race was also the first since the 1993 Australian Grand Prix not to feature refuelling during in-race pit stops, the first Grand Prix weekend since the 1997 Australian Grand Prix to have 24 initial entries and the first Grand Prix to have more than 22 starting drivers since the 1995 Japanese Grand Prix.